Let's start with his so-called "great-grandparents". They were the REAL Col. Edmund Scarburgh's GRANDparents - he was the grandson of Henry SR. and Elizabeth (probably Shaw rather than "Sham", an easy typo to make).
The Henry Scarburgh who married Mary Humberstone was his UNCLE, not his grandfather.
In spite of the ubiquitous myth that his mother was a "Butler", there is hard documentary evidence in the form of wills from various relatives that she was born a Smith.
*** ALL OF HIS WIVES ARE WRONG WRONG WRONG!!!!! ***
Col. Edmund Scarburgh married *once* and *once only*, a woman named Mary. She was *probably* born a Harmer and the widow of a Cade, although the reverse is also possible. NO CHARLETONS, LITTLETONS, OR POTTS!!!!!
Col. Edmund Scarburgh had *one* known mistress, a woman named Ann Taft or Toft, who bore him three daughters: Arcadia, Atalanta, and Annnabella - but NO SONS.
Col. Edmund Scarburgh had NO SON WILLIAM. His sons were *Col.* Charles Scarburgh (NOT the same Charles Scarburgh who married Anne and Katherine West), Littleton Scarburgh (godson of Ann (Southy) Littleton, died young, unmarried and without issue), and Col. Edmund Scarburgh III (who is often and carelessly muddled up with his father, and both of them with *Capt.* Edmund Scarburgh (the first Col.'s father).
There WERE Scarburghs around who were not in the direct line of descent - the aforementioned Charles Scarburgh (b. c. 1625), for instance. Some of them were probably cousins of one degree or another. Some might be *very* distant relatives from the lines that stayed put in Yorkshire or had moved to various other parts of England. And some might not be related at all (*anyone* from Scarborough, Yorkshire, could call themselves "Scarburgh" or any variant thereof).
Ann "Charlton" was not born with that name, and was NEVER known as "Mary". We DON'T KNOW what her birth name was. She married three times: 1) Anthony Huffe, 2) Anthony West, 3) Capt. Stephen Charlton - HE WAS NOT HER FATHER, HE WAS HER THIRD HUSBAND!!!!!
*She* never married any Scarburgh, but two of her children did. Her daughter Katherine West married 1) Ralph Barlow, 2) the Charles Scarburgh who was *not* a son of Col. Edmund, and 3) Major Edmund Bowman. And her son Lt. Col. John West married Matilda Scarburgh, who *was* a daughter of Col. Edmund.
Katherine West and Charles Scarburgh had a son Henry, who referenced his MATERNAL grandmother Ann by-then-Charlton - his MOTHER'S mother - in his will.
Mary (NOT THE SAME PERSON AS ANN CHARLTON) Scarburgh, widow of Col. Edmund, lived out her last years at the house of her grandson Anthony West - son of Matilda Scarburgh West.
It is ABSOLUTELY IMPOSSIBLE that Ann "Charlton" and Mary Cade/Harmer could be the same person, because THAT WOULD MAKE JOHN WEST AND MATILDA SCARBURGH HALF-SIBLINGS, AND THAT WAS *ILLEGAL*!!!!!