"The only village not incorporated, within the limits of the township, is situated near the southern boundary and is called Mechanicsville, or Frampton P. O. At present it contains a dry goods and grocery store, belonging to and kept by Mr. J. P. Kahle, a hotel known as the McCullough House, a blacksmith shop, a post-office, which has a daily mail, and is kept by Mr. Ed. M. McIntire; a wagon shop, and office of the justice of the peace, A. J. Frampton, esq., also several private residences. The post-office was so named in honor of William Frampton, esq., one of the oldest settlers of the place, and father of the present justice."
A.J. Frampton was Elizabeth Jane Frampton's brother, and the hotel McCullough House is almost definitely the building pictured above right (click to enlarge). The letters "ough" and "House" on the signpost can be identified.