Haim Wartski, HaCohen What I believe may be happening is that the R'Akiva's ancestry is from both Spain and Portugal. The other rabbis mentioned here https://www.geni.com/documents/view?doc_id=6000000177918049832 are were born in the Kingdom of Castille in Spain. The association of R' Yitzach HaCohen Katz with Rabbis Sabaa, Zacuto, and Caro could suggest that he too was born somewhere in Castille and that he, like them, was able to escape the forced conversion of 1497. So I believe it would be reasonable to presume that R' Yitzach was born at about the same time as the three rabbis (circa 1450) and that he was of Spanish descend but was in Portugal in 1497 when he was able to escape to Saloinka. It seems to me that his father was already in Salonica at that time, perhaps having opted to go there rather than Portugal (this remains to be fully understood). But in any case, it seems unlikely based on the above that R'Yitzach was born in Salonika, and if not, then his father too must have been in Castille around 1450. Along these same lines, if would seem unlikely for R' Yitzach's son R'Akiva of Uban to have been born before about 1470 and unlikely that he was born in Salonika. So I am presuming that all three generations were born in Castille roughly in 1430, 1450, and 1470. When R'Akiva of Uban went to Salonika is also a question: if he was already leaving Hungary for Prague in 1496, then he must have arrived in Hungary well before 1496, which means he must have departed Castile earlier than his father, probably first going to Salonika (perhaps traveling with his grandfather, or going to where his grandfather already was). I think what was throwing off this investigation were the birth years and places of R' Akiva the Elder and R' Yitzach previously posted on GENI and which now appear as being too early and in the wrong place, considering the alleged facts about R' Yitzach and the Portuguese conversions of 1497.