Probably not the son of Benjamin (Twin) Humphrey & Marie Humpphrey (Llewellyn) This Charles Humphrey was born 5 years before their marriage.
Most of the trees on Ancestry have him as the son of Daniel and his wife Hannah Wynne, but he isn't listed as one of their children in the Welsh Founders of PA.
Ref: https://www.google.com/books/edition/Welsh_Founders_of_Pennsylvania...