If he wasn't called "Isaac Bass of Roquist Swamp" during his lifetime, I don't think we should call him that now.
If other profile managers and other Isaac Bass descendants disagree, I will concede the point.
But I think he should remain ISAAC BASS, SR. as he is called in most Bass genealogies (and as he was called in his lifetime), to distinguish him from his son Isaac Bass, Jr
I tend to think that stuff is better kept in the overview page notes and the sources, rather than the name fields.
(That goes for the DNA info as well--let's keep it out of the name fields, please.)